Trazodone Qt Prolongation. Use trazodone with caution in patients with conditions that may increase the risk of QT prolongation including bradycardia AV block heart failure stress-related cardiomyopathy myocardial infarction stroke hypocalcemia or in patients receiving medications known to cause electrolyte imbalances. Possibly confounded by tachycardia Trazodone Associated with mild QTc prolongation in overdose Mirtazapine No clear QTc prolongation risk though it has been associated with a higher risk of SCD or ventricular arrhythmias than paroxetine in.
It is well recognized that tricyclic antidepressants particularly in an overdose may cause a variety of cardiac effects including QT interval prolongation on ECG 1. Escitalopram and QTc interval torsades de pointes TdP and sudden cardiac death in older adults. Antiarrhythmic agents were the first drugs associated with QT prolongation and ventricular arrhythmias.
Some drugs that prolong the QTQT c interval can cause torsade de pointes with sudden unexplained death.
Trazodone is known to prolong the QTQT c interval. Describes whether the FDA-approved product labelling includes mention of QT prolongation torsades de pointes or both. The case adds to the existing literature because it has a number of strengths namely that confounding drugs and alcohol were lacking trazodone exposure was confirmed by drug assay and early presentation to hospital gave a valuable. Possibly confounded by tachycardia Trazodone Associated with mild QTc prolongation in overdose Mirtazapine No clear QTc prolongation risk though it has been associated with a higher risk of SCD or ventricular arrhythmias than paroxetine in.