Trazodone Insomnia. Two recent reviews found that trazodone is the second-most prescribed agent for insomnia though most studies have been in depressed individuals. The effects of SSRIs compared with placebo are uncertain with too few studies to draw clear conclusions.
The tolerability and safety of antidepressants for insomnia is uncertain due to limited reporting of adverse events. Trazodone is used to treat major depressive disorder. Trazodone is usually administered multiple times per day but once-daily administration may be similarly effective.
Previously available brand formulations include Desyrel and an extended-release tablet form Oleptro.
Previously available brand formulations include Desyrel and an extended-release tablet form Oleptro. Uses Trazodone is an older drug that has been used to treat depression and severe anxiety for many years. Trazodone works by helping to restore the balance of a certain natural. Trazodone is only available as a generic drug.