Propofol. Propofol infusion syndrome PRIS is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofolIt can lead to cardiac failure rhabdomyolysis metabolic acidosis and kidney failure and is often fatal. Propofol slows the activity of your brain and nervous system.
Podawany jest w formie białej emulsji wodnej zawierającej olej sojowy i oczyszczone fosfolipidy z jaja kurzego. Propofol injectable emulsion USP is a sterile nonpyrogenic emulsion containing 10 mgmL of propofol suitable for intravenous administration. Propofol infusion syndrome may occur.
Propofol is used to help you relax before and during general anesthesia for surgery or other medical procedures.
How does it differ from more commonly used sedatives. When provided at an infusion rate exceeding 20 mL hr the caloric value of the propofol in combination with feeds can lead to significant overfeeding. Propofol Dreams Last Update. The clinical features of propofol infusion syndrome PRIS are acute refractory bradycardia leading to asystole in the presence of one or more of the following.