Prednisone Qt Prolongation. The risk is greater in people who are seriously ill with structural heart disease electrolyte abnormalities or taking other medications that also prolong the QT interval. In post marketing experience QT prolongation.
Abiraterone acetate Zytiga is indicated with prednisone or prednisolone for the treatment of metastatic castration-resistant prostate cancer. X The prevalence of left bundle branch block LBBB in general population is commonly low but its prevalence significant increase in patients with chronic heart failure HF 1. Recent analyses have demonstrated that COVID-19 patients have a significant incidence of acute HF while those with a history of chronic HF are prone to developing acute decompensation.
Therefore precaution should be taken when using Levofloxacin with concomitant drugs that can result in prolongation of the QT interval eg Class IA or Class III antiarrhythmics or in patients with risk factors for torsade de pointes eg known QT prolongation uncorrected hypokalemia see Warnings and Precautions 511.
UpToDate electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine Allergy and Immunology Cardiovascular Medicine Emergency Medicine Endocrinology and Diabetes Family Medicine Gastroenterology and Hepatology Hematology Infectious Diseases Nephrology and Hypertension Neurology Obstetrics Gynecology and Women. This part of the eMedTV library lists other drugs that may increase the risk of QT prolongation and describes the seriousness of the condition. Abiraterone acetate Zytiga is indicated with prednisone or prednisolone for the treatment of metastatic castration-resistant prostate cancer. Moderate Corticosteroids may potentiate the hypokalemic effects of epinephrine.