Prednisone Glucocorticoid. A recent editorial in the Journal of Clinical Endocrinology Metabolism by Dr. After cell surface receptor attachment and cell entry prednisone enters the nucleus where it binds to and activates specific nuclear receptors resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
Prednisone is a glucocorticoid. Prednisone and Prednisolone are glucocorticoid medications that are prescribed for many uses including reducing inflammation suppressing the immune system treating some types of cancer and as a replacement when the body is not making enough glucocorticoid on its own. 5-60 mgday PO in single daily dose or divided q6-12hr.
Pills may be taken as often as 4 times a day or as infrequently as once every other day.
It consists of an outer cortex adrenal cortex and an inner medulla adrenal. The amount of time it takes to taper off prednisone depends on the disease being treated the dose and duration of use and other medical considerations. Prednisone is a glucocorticoid. If you have been instructed by your doctor be prepared to give yourself an emergency shot of glucocorticoid or to increase your dosage of oral glucocorticoid.