Dapsone. Dapsone belongs to a class of drugs known as sulfones. As a structural analog of p-aminobenzoic acid dapsone inhibits dihydropteroate synthase DHPS an enzyme important in folate synthesis resulting in a depletion of the folate pool and a reduction in the amount of thymidylate available for DNA synthesis.
It works by decreasing swelling inflammation and stopping the growth of bacteriaThis medication will not. Dapsone is used to treat dermatitis herpetiformis a skin condition and leprosy. It is not known if Dapsone is safe and effective in children younger than 1 month of age.
It is used to treat a skin problem called dermatitis herpetiformis.
Dapsone belongs to a class of drugs called Antileprosy Agents. Dapsone may also be. Using selective cytochrome P450 CYP inhibitors and clinical concentrations 4 microM of dapsone DDS we found a major contribution of CYP2C9 and little or no contribution or 10 of CYP3A4 and CYP2E1 to dapsone N-hydroxylation DDS-NHY in human liver microsomes. Dapsone is a synthetic derivative of diamino-sulfone with anti-inflammatory and anti-bacterial properties.