Clopidogrel Label. A prospective multicenter randomized open-label trial to compare efficacy and safety of clopidogrel versus ticagrelor in stabilized patients with acute myocardial infarction after percutaneous coronary intervention. It is practically insoluble in water at neutral pH but freely soluble at pH 1.
Original Article from The New England Journal of Medicine Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation. Clopidogrel bisulfate is a white to off-white powder. Patients in the group receiving clopidogrel plus aspirin were given a 600-mg loading dose of clopidogrel followed by 75 mg per day from day 2 to day 90 and a dose of open-label aspirin that.
Trial Design and Oversight.
It is available in brand and generic form. Each tablet contains hydrogenated castor oil hydroxypropylcellulose mannitol microcrystalline cellulose and polyethylene glycol 6000 as inactive ingredients. The AFIRE trial was a multicenter randomized open-label parallel-group trial that evaluated the noninferiority of XARELTO monotherapy 10 mg once daily for CrCl 1549 mLmin or 15 mg for CrCl 50 mLmin versus the combination of XARELTO same dose plus an antiplatelet agent aspirin 81 mg or 100 mg once daily or clopidogrel 75 mg or 50 mg. The POPular TAVI trial is an investigator-initiated parallel-group randomized open-label trial performed at 17 European sites 9.