Bortezomib. Bortezomib side effects. Grade 3 or 4 non-hematologic drug related toxicity.
By interfering with its function this can lead to apoptosis cell. It blocks the proteasome which is a system in cells that breaks down proteins that are no longer needed. Postmarket Drug Safety Information for Patients and Providers.
Bortezomib side effects.
Blocking the proteasome system results in a build-up of unwanted proteins that causes the cells to die. Velcade bortezomib Cytoxan cyclophosphamide and dexamethasone VCD or CyBorD. The active substance in Velcade bortezomib is a proteasome inhibitor. Grade 3 or 4 non-hematologic drug related toxicity.