Atorvastatin Qt Prolongation. The recommendations listed in this document are whenever possible evidence based. QT prolongation can rarely cause serious rarely fatal fastirregular heartbeat and other symptoms such as severe dizziness fainting that need medical attention right away.
Hypoglycemia with disopyramide and hypotension and acute kidney injury with calcium channel blockers metabolized by CYP3A4 eg. Founded by Woosley in 1999 the online resource is devoted to the safe use of medicines particularly those known to cause a heart rhythm problem called QT interval prolongation which can increase the risk of torsades de pointes a heart arrhythmia that can result in sudden cardiac death. Fluoroquinolones have the potential to cause QT prolongation and possibly torsade de pointes TdP by blocking human cardiac potassium K channel currents28775 33146 The potency of this blockade varies among the quinolones with ciprofloxacin appearing to have a lower potency than other quinolones such as levofloxacin33146 Based on.
Macrolides can prolong the QT interval.
At risk of QT interval prolongation this includes women with cardiomyopathy sinus bradycardia arrhythmias hypokalaemia hypomagnesaemia hypocalcaemia and those taking other drugs known to cause QT interval prolongation such as tricyclic antidepressants antipsychotics or antiarrhythmics. People with a history of QT prolongation or ventricular cardiac arrhythmia including Torsades de pointes. Founded by Woosley in 1999 the online resource is devoted to the safe use of medicines particularly those known to cause a heart rhythm problem called QT interval prolongation which can increase the risk of torsades de pointes a heart arrhythmia that can result in sudden cardiac death. May interact with a number of medicines including warfarin oral hypoglycemics terfenadine ergotamine pimozide herbal supplements and other anti-infectives.