Atorvastatin Pregnancy Category. 246 moderate drug interactions 711 brand and generic names. Iodine supplements Zoledronic acid Atorvastatin.
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Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A reductase the enzyme which catalyzes the conversion of HMG-CoA to mevalonate a key step in cholesterol synthesisAtorvastatin also increases the number of LDL receptors on hepatic cell surfaces to enhance uptake and catabolism of LDL and reduces LDL.
The human pregnancy-specific glycoproteins PSGs are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Atorvastatin Pregnancy Warnings This drug crosses the rat placenta and reaches levels in the fetal liver equivalent to that of maternal plasma. Atorvastatin is indicated as an adjunct to diet for reduction of elevated total cholesterol total-C LDL-cholesterol LDL-C apolipoprotein B and triglycerides in adults adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia heterozygous variant or combined mixed hyperlipidaemia Corresponding. Buy Atorvastatin 20 MG Tablet Online.