Alprazolam Receptor. Benzodiazepines expose users to risks of abuse misuse and addiction which can lead to overdose or death. Alprazolam like other benzodiazepines acts through the GABA A receptor.
Racial or Ethnic Groups. There are three receptors of the gamma-aminobutyric acidThe two receptors GABA-α and GABA-ρ are ion channels that are permeable to chloride ions which reduces. Flumazenil a benzodiazepine receptor antagonist is indicated for partial or complete reversal of the depressive effects of benzodiazepines and may be useful in overdose situations see Flumazenil monograph.
The reported relative potencies in benzodiazepine receptor binding.
Alprazolam was patented in 1971 and approved for medical use in the United States in 1981. This peer-reviewed international journal publishes basic and clinical contributions from all disciplines and. Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic thalamic and hypothalamic regions of the central nervous system CNS. Alprazolam is a Schedule IV controlled substance and is a common drug of abuse.